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  1. Imamura T, Higuchi H, Sekine KT, Yamashita T, and Takahashi H. High concentrations of sucrose induce overwintering bud formation in gentian plantlets cultured in vitro. Plant Biotechnol. (in press)
  2. Imamura T, Higuchi H, and Takahashi H. (2013) Dehydrins are highly expressed in overwintering buds and enhance drought and freezing tolerance in Gentiana triflora. Plant Sci. 213, 55-66.[PubMed]
  3. Nakatsuka T, Yamada E, Takahashi H, Imamura T, Suzuki M, Ozeki Y, Tsujimura I, Saito M, Sakamoto Y, Sasaki N, and Nishihara M. (2013) Genetic engineering of yellow betalain pigments beyond the species barrier. Sci. Rep. 3, 1970. doi: 10.1038/srep01970. [PubMed]
  4. Ito K, Takahashi H, Umekawa Y, Imamura T, Kawasaki S, Ogata T, Kakizaki Y, and Seymour RS. (2013) Metabolite profiling reveals tissue- and temperature-specific metabolomic responses in thermoregulatory male florets of Dracunculus vulgaris (Araceae). Metabolomics 9, 919-930.[link]
  5. Hashida SN, Takahashi H, Takahara K, Kawai-Yamada M, Kitazaki K, Shoji K, Goto F, Yoshihara T, and Uchimiya H. NAD+ Accumulation during Pollen Maturation in Arabidopsis Regulating Onset of Germination. Mol Plant. 6, 216-25.[PubMed]
  1. Takahashi H, Yamada H, Yoshida C, and Imamura T. Modification of light quality improves growth and medicinal quality of clonal explants derived from herbal plant Gentiana. Plant Biotechnol. 29, 315-318. [link]
  2. Konno N, Takahashi H, Nakajima M, Takeda T, and Sakamoto Y. Characterization of β-N-acetylhexosaminidase (LeHex20A), a member of glycoside hydrolase family 20, from Lentinula edodes (shiitake mushroom). AMB Express. 2, 29. [PubMed]
  3. Takahashi H, Imamura T, Miyagi A, and Uchimiya H. (2012). Comparative metabolomics of developmental alterations caused by mineral deficiency during in vitro culture of Gentiana triflora. Metabolomics. 8, 154-163. [link]
  1. Imamura T, Nakatsuka T, Higuchi A, Nishihara M, and Takahashi H. (2011). The gentian orthologs of the FT/TFL1 gene family control floral initiation in Gentiana. Plant Cell Physiol. 52, 1031-1041.[PubMed]
  2. Miyagi A, Takahara K, Kasajima I, Takahashi H, Kawai-Yamada M, and Uchimiya H. (2011). Fate of 13C in metabolic pathways and effects of high CO2 on the alteration of metabolites in Rumex obtusifolius L. Metabolomics. 7, 524-535.[link]
  1. She KC, Kusano H, Koizumi K, Yamakawa H, Hakata M, Imamura T, Fukuda M, Naito N, Tsurumaki Y, Yaeshima M, Tsuge T, Matsumoto K, Kudoh M, Itoh E, Kikuchi S, Kishimoto N, Yazaki J, Ando T, Yano M, Aoyama T, Sasaki T, Satoh H, and Shimada H. (2010). A novel factor FLOURY ENDOSPERM2 is involved in regulation of rice grain size and starch quality. Plant Cell 22, 3280-3294. [PubMed]
  2. Imamura T, Yasuda M, Kusano H, Nakashita H, Ohno Y, Kamakura T, Taguchi S, and Shimada H. (2010). Acquired resistance to the rice blast in transgenic rice accumulating the antimicrobial peptide thanatin. Transgenic Res. 19, 15-424.[PubMed]
  3. Takahara K, Kasajima I, Takahashi H, Hashida SN, Itami T, Onodera H, Toki S, Yanagisawa S, Kawai-Yamada M, and Uchimiya H. (2010). Metabolome and photochemical analysis of rice plants overexpressing Arabidopsis NAD kinase gene. Plant Physiol. 152, 1863-1873.[PubMed]
  4. Miyagi A, Takahashi H, Takahara K, Hirabayashi T, Nishimura Y, Tezuka T, Kawai-Yamada M, and Uchimiya H. (2010). Principal component and hierarchical clustering analysis of metabolites in destructive weeds; Polygonaceous plants. Metabolomics. 6, 146-155.[Link]
  5. Hashida SN, Itami T, Takahashi H, Takahara K, Nagano M, Kawai-Yamada M, Shoji K, Goto F, Yoshihara T, and Uchimiya H. (2010). Nicotinate/nicotinamide mononucleotide adenyltransferase-mediated regulation of NAD biosynthesis protects guard cells from reactive oxygen species in ABA-mediated stomatal movement in Arabidopsis. J. Exp. Bot. 61, 3813-3825.[PubMed]
  6. Takahashi M, Takahashi H, Nakano Y, Konishi T, Terauchi R, and Takeda T. (2010). Characterization of a cellobiohydrolase (MoCel6A) produced by Magnaporthe oryzae. Appl. Environ. Microbiol. 76, 6583-6590.[PubMed]
  1. Takahashi H, Takahara K, Hashida SN, Fujimori T, Kawai-Yamada M, Yamaya T, Yanagisawa S, and Uchimiya H. (2009). Pleiotropic modulation of carbon and nitrogen metabolism in Arabidopsis plants overexpressing NAD kinase2 gene. Plant Physiol. 151, 100-113.[PubMed]
  2. Takahashi H, Munemura I, Nakatsuka T, Nishihara M, and Uchimiya H. (2009). Metabolite profiling by capillary electrophoresis mass spectrometry reveals aberrant putrescine accumulation associated with idiopathic symptoms of gentian plants. J. Hortic. Sci. Biotechnol. 84, 113-119. [Link]
  3. Yoda H, Fujimura K, Takahashi H, Munemura I, Uchimiya H, and Sano H. (2009). Polyamines as a common source of hydrogen peroxide in host- and nonhost-hypersensitive response during pathogen infection. Plant Mol. Biol. 70, 103-112. [PubMed]
  4. Hashida SN, Takahashi H, and Uchimiya H. (2009). The role of NAD biosynthesis in plant development and stress responses. Ann. Bot. 103, 819-824. [PubMed]
  5. Tsujimoto-Inui Y, Naito Y, Sakurai N, Suzuki H, Sasaki R, Takahashi H, Ohtsuki N, Nakano T, Yanagisawa S, Shibata D, Uchimiya H, Shinshi H, and Suzuki K. (2009). Functional genomics of the Dof transcription factor family genes in suspension-cultured cells of Arabidopsis thaliana. Plant Biotechnol. 26, 15-18.[Link]
  1. Takahashi H, Matsumura H, Kawai-Yamada M, and Uchimiya H. (2008). The cell death factor, cell wall elicitor of rice blast fungus (Magnaporthe grisea) causes metabolic alterations including GABA shunt in rice cultured cells. Plant Sig. Behav. 11, 945-953.[PubMed]
  2. Takahashi H, Uchimiya H, and Hihara Y. (2008). Difference in metabolite levels between photoatotrophic and photomixotrophic cultures of Synechocystis sp. PCC 6803 examined by capillary electrophoresis electrospray ionization mass spectrometry. J. Exp. Bot. 59, 3009-3018. [PubMed]
  3. Nakatsuka T, Sato K, Takahashi H, Yamamura S, and Nishihara M. (2008). Cloning and characterization of the UDP-glucose:anthocyanin 5-O-glucosyltransferase gene from blue-flowered gentian. J. Exp. Bot. 59, 1241-1252. [PubMed]
  4. Negi J, Matsuda O, Nagasawa T, Oba Y, Takahashi H, Kawai-Yamada M, Uchimiya H, Hashimoto M, and Iba K. (2008). CO2 regulator SLAC1 and its homologues are essential for anion homeostasis in plant cells. Nature 452, 483-486. [PubMed]
  5. Imamura T, Yamamoto N, Tamura A, Murabayashi S, Hashimoto S, Shimada H, and Taguchi S. (2008). NMR based structure-activity relationship analysis of an antimicrobial peptide, thanatin, engineered by site-specific chemical modification: Activity improvement and spectrum alteration. Biochem Biophys Res Commun. 369, 609-615. [PubMed]
  6. Furukawa T, Imamura T, Kitamoto HK, and Shimada H. (2008). Rice exonuclease-1 homologue, OsEXO1, that interacts with DNA polymerase lambda and RPA subunit proteins, is involved in cell proliferation. Plant Mol Biol. 66, 519-531. [PubMed]
  1. Hashida SN, Takahashi H, Kawai-Yamada M, and Uchimiya H. (2007). Arabidopsis thaliana nicotinate/nicotinamide mononucleotide adenyltransferase (AtNMNAT) is required for pollen tube growth. Plant J. 49, 694-703. [PubMed]
  2. Imamura T, Kusano H, Kajigaya Y, Ichikawa M, and Shimada H. (2007). A rice dihydrosphingosine C4 hydroxylase (DSH1) gene, which is abundantly expressed in the stigmas, vascular cells and apical meristem, may be involved in fertility. Plant Cell Physiol. 48, 1108-1120.[PubMed]
  3. Takahashi H, Watanabe A, Tanaka A, Hashida SN, Kawai-Yamada M, Sonoike K, and Uchimiya H. (2006). Chloroplast NAD kinase is essential for energy transduction through the xanthophyll cycle in photosynthesis. Plant Cell Physiol. 47, 1678-1682 [PubMed].
  4. Takahashi H, Hayashi M, Goto F, Sato S, Soga T, Nishioka T, Tomita M, Kawai-Yamada M, and Uchimiya H. (2006). Evaluation of metabolic alteration in transgenic rice overexpressing dihydroflavonol-4-reductase. Ann. Bot. 98, 819-825. [PubMed]
  5. Yoda H, Hiroi Y, Sano H. (2006). Polyamine oxidase is one of the key elements for oxidative burst to induce programmed cell death in tobacco cultured cells. Plant Physiol. 142, 193-206.[PubMed]
  6. Tanaka N, Takahashi H, Kitano H, Matsuoka M, Akao S, Uchimiya H, and Komatsu S. (2005). Proteome approach to characterize the methylmalonate-semialdehyde dehydrogenase that is regulated by gibberellin. J. Proteome Res. 4, 1575-1582. [PubMed]
  7. Hayashi M, Takahashi H, Kawai-Yamada M, Tezuka T, and Uchimiya H. (2005). Enhanced dihydroflavonol-4-reductase activity and NAD homeostasis leading to cell death tolerance in transgenic rice. Proc. Natl. Acad. Sci. U. S. A. 102, 7020-7025. [PubMed]